1. Education

　　M.Sc. 07.1987 Organic Synthesis, Lanzhou University, China

　　B. Sc. 07.1984 Chemistry, Sichuan University, China

　　2. Research Experience

　　Postdoc: 01.1995-10.1996, Chemistry Department, Beijing University

　　Associate Professor: 11.1996-11.1997, Chengdu Institute of Biology, Chinese Academy of Sciences

　　Professor: 11.1997-Present, Chengdu Institute of Biology, Chinese Academy of Sciences

　　Sichuan Provincial Academic and Technical Leader, 2003

　　Award for Excellent Scientist in Chengdu, 2003

　　7th Award for Young Scientists of Sichuan Province, 2004

　　1st Class Award of Sichuan Province for Science and Technology, 2/9, 2013

　　1. Guoyou Li, Tao Yang, Yinggang Luo, Xiaozhen Chen, Dongmei Fang, Guolin Zhang*, Brevianamide J, a new indole alkaloid dimer from fungus Aspergillus versicolor, Organic Letters, 2009, 11 (16): 3714-3717

　　2. Zhijun Wu, Xiaozhen Chen, Dongmei Fang, Huayi Qi, Weijian Ren, Guolin Zhang*, Analysis of phenolic glycosides from Ilex litseaefolia using electrospray ionization quadrupole time-of-flight mass spectrometry, Rapid Commun. Mass Spectrom. 2009, 23: 3881–3885

　　3. Zhijun Wu, Jianxin Pu, Limei Li, Dongmei Fang, Huayi Qi, Guoyou Li, Jianzhong Chen, Handong Sun, Guolin Zhang*, Electrospray tandem mass spectrometry of longipedlactone triterpenoids, J. Mass Spectrom. 2010, 45: 451-455.

　　4. Guoyou Li, Limei Li, Tao Yang, Xiaozhen Chen, Dongmei Fang, Guolin Zhang*, Four New Alkaloids, Brevianamides O–R, from the fungus Aspergillus versicolor, Helvetica Chimia Acta, 2010, 93 (10): 2075-2080

　　5. Zhijun Wu, Dongmei Fang, Dan Han, Guoyou Li, Xiaozhen Chen, Huayi Qi, Guolin Zhang*, Analysis of sesterterpenoids from Aspergillus terreus using ESI-QTOF and ESI-IT, Phytochemical Analysis, 2010, 21 (4): 374-383

　　6. Chun Feng, Bogang Li, Xiaoping Gao, Huayi Qi, Guolin Zhang*, A new triterpene and an antiarrhythmic liriodendrin from Pittosporum brevicalyx, Archives of Pharmacal Research，2010, 33 (12): 1927-1932

　　7. Changsong Li, Hongwei Yu, Xiaozhen Chen, Xiaoqing Wu, Guoyou Li, Guolin Zhang*, Three new eudesmanolides from Camchaya loloana, Helvetica Chimia Acta, 2011, 94 (1): 105-110

　　8. Lijuan Yang, Qianfeng Chen, Fei Wang*, Guolin Zhang*，Antiosteoporotic compounds from seeds of Cuscuta chinensis, Journal of Ethnopharmacology, 2011, 135: 553–560

　　9. Zhijun Wu, Dongming Sun, Jianzhong Chen, Xiaozhen Chen, Dongmei Fang, Na Li, Ping Cheng，Guolin Zhang*, Analysis of cipadesin limonoids from Cipadessa cinerascens using electrospray ionization quadrupole time-of-flight tandem mass spectrometry and quantum chemical calculations, Rapid Commnications in Mass Spectrometry, 2012, 26: 563–571

　　10. Yinggang Luo, Min Zhou, Qi Ye, Guolin Zhang*, Dihydroagarofurna derivatives from dried roots of Tripterygium wilfordii, Journal of Natural Produsts, 2012, 75: 98-102

　　11. Danfeng Lu, Lijuan Yang, Fei Wang*, Guolin Zhang*, Inhibitory effect of luteolin on estrogen biosynthesis in human ovarian granulosa cells by suppression of aromatase (CYP19), Journal of Agricultural and Food Chemistry, 2012, 60 (34): 8411-18.

　　12. Danfeng Lu, Lijuan Yang, Qilin Li, Xiaoping Gao, Fei Wang*, Guolin Zhang*, Egonol gentiobioside and egonol gentiotrioside from Styrax perkinsiae promote the of estrogen by aromatase, European Journal of Pharmacology, 2012, 691: 275–282

　　13. Guobo Xu, Limei Li, Tao Yang, Guolin Zhang*, Guoyou Li*, Chaetoconvosins A and B, Alkaloids with New Skeleton from Fungus Chaetomium convolutum, Organic Letters, 2012, 14 (23): 6052–6055

　　14. Lijuan Yang, Danfeng Lu, Jiajia Guo, Xianli Meng, Guolin Zhang*, Fei Wang*，Icariin from Epimedium brevicornum Maxim promotes the biosynthesis of estrogen by aromatase (CYP19)，Journal of Ethnopharmacology, 2013, 145: 715-721.

　　15. Puzhao Zhang, Fei Wang, Lijuan Yang, Guolin Zhang*, Pregnane alkaloids from Sarcococca hookeriana var digyna, Fitoterapia, 2013,89:143-148

　　16. Yuan Lin, Fei Wang, Lijuan Yang, Ze Chun, Jinku Bao, Guolin Zhang*, Anti-inflammatory phenanthrene derivatives from stems of Dendrobium denneanum, Phytochemistry,2013, 95: 242-251

　　17. Xiang Pu, Xixing Qu, Fei Chen, Jinku Bao, Guolin Zhang*, Yinggang Luo*, Endophytic fungus Trichoderma atroviride LY357: Isolation, identification, and camptothecin production, Applied Microbiology and Biotechnology, 2013, 97: 9365–9375

　　18. WenChen Pu, Guan-Min Mu, GuoLin Zhang*, Chun Wang*, Copper-Catalyzed Decarboxylative Intramolecular C-O Coupling: Synthesis of 2-Arylbenzofuran from 3-Arylcoumarin, RSC Advances, 2014, 4: 903–906

　　19. Zhengfu Tai, Yujiao He, Yuan Lin, Junmei Huang, Jiajia Guo, Lijuan Yang, Guolin Zhang*, Fei Wang*, Luteolin Sensitizes the Antiproliferative Effect of Interferon α/β by Activation of JAK/STAT Pathway through PKA-Mediated Inhibition of SHP-2 in cancer cells, Cell Signaling, 2014, 26: 619-628

　　20. Guoyong Luo, Min Zhou, Yan Liu, Qi Ye, Jian Gu, Tianfang Huang, Guolin Zhang, Yinggang Luo*，3-Formyl-2-arylbenzofurans from the aerial parts of Itea ilicifolia，Phytochemistry Letters, 2014, 10: 19–22

　　21. Jiajia Guo, Yun Yuan, Danfeng Lu, Liang Xiong, Jiangong Shi, Lijuan Yang, Xiaohong Yuan, Guolin Zhang*, Fei Wang*, Two natural products, trans-phytol and (22E)-ergosta-6,9,22-triene-3β,5α,8α-triol, inhibit the biosynthesis of estrogen in human ovarian granulosa cells by aromatase (CYP19), Toxicology and Applied Pharmacology, 2014, 279 (1): 23-32

　　22. Yinggang Luo, Xiang Pu, Guoyong Luo, Min Zhou, Huayi Qi, Qi Ye, Yan Liu, Guolin Zhang*, Nitrogen-containing dihydro-β-agarofuran derivatives mined from the dried roots of Tripterygium wilfordii, Journal of Natural Products, 2014,77 (7): 1650-1657 (JUL 2014)

　　23. Wenchen Pu, Yuan Lin, Jianshuo Zhang, Fei Wang, Chun Wang, Guolin Zhang*, 3-Arylcoumarins: Synthesis and potent anti-inflammatory activity, Bioorganic & Medicinal Chemistry Letters, 2014, 24: 5432-5434

　　24. Qinggang Mei, Chun Wang, Weicheng Yuan, Guolin Zhang*, Selective methylation of kaempferol via benzylation and deacetylation of kaempferol acetates, Beilstein Journal of Organic Chemistry, 2015, 11: 288–293. doi:10.3762/bjoc.11.33

　　25. Tian Cai, Yinggang Luo, Min Zhou, Zhijun Wu*, Dongmei Fang, Guolin Zhang?, Analysis of sesquiterpene pyridine alkaloids using ESI–MS/MS: The product ion at m/z 310 formed by an ion–dipole intermediate，International Journal of Mass Spectrometry, 2015, 376: 54-57

　　26. Tian Cai, Yinggang Luo, Min Zhou, Dan Wang, Zhijun Wu*, Dongmei Fang, and Guolin Zhang*. Untargeted analysis of sesquiterpene pyridine alkaloids from the dried roots of Tripterygium wilfordii using high-performance liquid chromatography/electrospray ionization tandem mass spectrometry. Rapid Communications in Mass Spectrometry, 2015, 29: 965-972.

　　27. Qinggang Mei, Chun Wang, Zhigang Zhao, Weicheng Yuan, Guolin Zhang*, Synthesis of icariin from kaempferol through regioselective methylation and para-Claisen-Cope rearrangement, Beilstein Journal of Organic Chemistry, 2015, 11: 1220–1225. doi:10.3762/bjoc.11.135

　　28. Yujiao He, Junmei Huang, Ping Wang, Xiaofei Shen, Sheng Li, Lijuan Yang, Wanli Liu, Apichart Suksamrarn, Guolin Zhang*, Fei Wang*, Emodin potentiates the antiproliferative effect of interferon ?/? by activation of JAK/STAT pathway signaling through inhibition of the 26S proteasome, Oncotarget, 2016, 7 (4): 4664-4679.

　　29. Puzhao Zhang, Yamei Zhang, Jian Gu, Guolin Zhang*, Two new alkaloids from Melodinus hemsleyanus（川山橙）, Natural Product Research, 2016, 30 ( 2): 162-167.

　　30. Guoyong Luo, Qi Ye, Baowen Du, Fei Wang, Guolin Zhang*, Luo Yinggang*, Iridoid glucosides and diterpenoids from Caryopteris glutinosa, Journal of Natural Products, 2016, 79: 886-893

　　31. Wenchen Pu, Yun Yuan, Danfeng Lu, Xin Wang, Chun Wang, Fei Wang, Guolin Zhang*, 2-Phenylbenzo[b]furans: synthesis and promoting activity on estrogen biosynthesis，Bioorganic & Medicinal Chemistry Letters, 2016, 26: 5497-5500.

　　32. Xianyan Shen, Qiang Zhou, Wei Xiong, Wenchen Pu, Guolin Zhang*, Chun Wang*, Synthesis of 5-subsituted flavonols via Algar-Flynn-Oyamada (AFO) reaction: the mechanistic implication, Tetrahedron, 2017, 73: 4822-4829

　　33. Orawan Wonganan, Yujiao He, Xiaofei Shen, Kanjana Wongkrajang, Apichart Suksamrarn, Guolin Zhang*, Fei Wang*, 6-Hydroxy-3-O-methyl-kaempferol 6-O-glucopyranoside potentiates the antiproliferative effect of interferon α/β by promoting the activation of JAK/STAT signaling through the inhibition of SOCS3 in hepatocellular carcinoma cells, Toxicology and Applied Pharmacology, 2017, 336:31-39

　　34. Jinzhi Zhao, Yun Yang, Mengyao Yu, Ke Yao, Xia Luo, Hua-Yi Qi, Guolin Zhang*, Yinggang Luo*, Cytotoxic Lanostane-type C31 Triterpeniod Derivatives from the Fruiting Bodies of Cultivated Fomitopsis palustris, Phytochemistry, 2018, 152：10-21