| Jian Liao | |
| Title: | |
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| Phone: | |
| Highest Education: | |
| Email: | jliao@cib.ac.cn |
Education and Appointments:
M. Sc., Chengdu Institute of Organic Chemistry, CAS, 1996-1999 (with Professor Daimo Chen)
Ph.D., Chengdu Institute of Organic Chemistry, CAS, 1999-2002(with Professor Jingen Deng)
Professor, Chengdu Institute of Organic Chemistry, CAS, 2006-2010
Professor, Chengdu Institute of Biology, CAS, 2010-
Research Interest
(2) Asymmetric Metal Catalysis
(3) Synthetic Methodologies of Natural Products/Bio-active Compounds
Public Services
Honors
Seleted Publication
(31) Liyin Jiang, Tao Jia, Min Wang, Jian Liao, and Peng Cao* “Pd-Catalyzed Enantioselective Hydroalkoxylation of Alkoxyallenes with Phenol for Construction of Acyclic O,O-Acetals” Org. Lett., 2015, 17 ,1070.
(30) Tao Jia, Peng Cao, Ding Wang, Yazhou Lou, Jian Liao* “Copper-Catalyzed Asymmetric Three-Component Borylstannation: Enantioselective Formation of C-Sn Bond” Chem. Eur. J. 2015, 21, 4918.
(29) Juanjuan Wang, Bing wang, Peng Cao, Jian Liao* “Rhodium Catalyzed Asymmetric 1,4-Addition of Arylboronic Acids to β,γ-Unsaturated α-Keto Ester Using Chiral tert-Butanesulfinylphosphines Ligands” Tetrahedron Lett. 2014, 55, 3450.
(28) Juanjuan Wang, Min Wang, Peng Cao, Liyin Jiang, Guihua Chen, Jian Liao* “Rh-Catalyzed Asymmetric Arylation ofβ,γ-Unsaturated α-Ketoamides for the Construction of Nonracemic γ,γ-Diarylcarbonyls” Angew. Chem. Int. Ed. 2014, 53, 6673. (Highlighted by Synfacts, 2014, 1042)
(27) Le Du, Peng Cao, Jian Liao* “Bifunctional Ligand Promoted Pd-Catalyzed Asymmetric Allylic Etherification/Amination” Acta Chimica Sinica 2013, 71, 1239.
(26) Le Du, Peng Cao, Junwei Xing, Yazhou Lou, Liyin Jiang, Liangchun Li, Jian Liao* “Hydrogen Bond Promoted Palladium-Catalysis: Allylic Alkylation of Indoles with Unsymmetrical 1,3-Disubstituted Allyl Acetates Using Chiral Bis(sulfoxide) Phosphine Ligands” Angew. Chem. Int. Ed. 2013, 52, 4207.
(25) Jiangyang Gui, Guihua Chen, Peng Cao, Jian Liao* “Rh(I)-catalyzed asymmetric addition of arylboronic acids to NH isatins” Tetrahedron: Asymmetry 2012, 23,554.
(24) Junwei Xing, Peng Cao, Jian Liao* “Chiral SO/P hybrid ligands: an enantioselective switch in palladium-catalyzed asymmetric allylic etherifications” Tetrahedron: Asymmetry 2012, 23, 527.
(23) Guihua Chen, Jiangyang Gui, Peng Cao, Jian Liao* “Chiral sulfoxideeolefin ligands: tunable stereoselectivity in Rh-catalyzed asymmetric 1,4-additions” Tetrahedron 2012, 68, 3220.
(22)Guihua Chen, Junwen Xing, Peng Cao, Jian Liao* “Rh/chiral sulfinylphosphine catalyzed asymmetric 1,4-addition of arylboronic acids to chalcones” Tetrahedron 2012, 68, 5908.
(21)Junwen Xing, Guihua Chen, Peng Cao and Jian Liao* “Rhodium-Catalyzed Asymmetric Addition of Arylboronic Acids to Indolylnitroalkenes” Eur. J. Org. Chem. 2012, 1230.
(20) Xiangyang Zhang, Guihua Chen, Peng Cao, Jibing Liu and Jian Liao* “Rhodium-Catalyzed Michael Addition of Arylboronic Acids to 3-Alkylenyloxindoles: Asymmetric Synthesis of Functionalized Oxindoles” Tetrahedron Lett. 2012, 53, 438.
(19) Guihua Chen, Jiangyang Gui, Liangchun Li and Jian Liao* “Chiral Sulfoxide-Olefin Ligands: Completely Switchable Stereoselectivity in the Rh-Catalyzed Asymmetric Conjugate Additions” Angew. Chem. Int. Ed. 2011, 50, 7681 (hot paper, Highlight by Synfacts, 2011, 1193 ).
(18) Fuzhong Han, Guihua Chen, Xiangyang Zhang, and Jian Liao* “Chiral Hetero-Disulfoxide Ligands in Rhodium-Catalyzed Asymmetric 1,4-Addition of Arylboronic Acids to Chromenones” Eur. J. Org. Chem. 2011, 2928.
(17) Feng Lang, Guihua Chen, Liangchun Li, Junwen Xing, Fuzhong Han, Linfeng Cun, and Jian Liao* “Rhodium-Catalyzed Highly Enantioselective Addition of Arylboronic Acids to 2-Nitrostyrenes by tert-Butanesulfinylphosphine Ligand” Chem. Eur. J. 2011, 5242 (Highlight by Synfacts, 2011, 882).
(16) Jibing Liu, Guihua Chen, Junwei Xing and Jian Liao* “tert-Butanesulfinylthioether ligands: synthesis and application in palladium-catalyzed asymmetric allylic alkylation” Tetrahedron: Asymmetry 2011, 22, 575.
(15) Xiangyang Zhang, Jun Chen, Fuzhong Han, Linfeng Cun, and Jian Liao* “Rhodium-Catalyzed Enantioselective Conjugate Addition of Sodium Tetraaryl-borates to 2,3-Dihydro-4-Pyridones and 4-Quinolones by Using (R,R)-1,2-bis(tert-butylsulfinyl)benzene as Ligand” Eur. J. Org. Chem. 2011, 1443.
(14) Fuzhong Han, Jun Chen, Xiangyang Zhang, Jibing Liu, Linfeng Cun, Jin Zhu, Jingen Deng, and Jian Liao* “Rhodium-catalyzed asymmetric addition of arylboronic acids to γ-phthalimido-substituted-α, β-unsaturated carboxylic acid esters: an approach to γ-amino acids” Tetrahedron Lett. 2011, 52, 830.
(13) Jun Chen, Junmin Chen, Feng Lang, Xiangyang Zhang, Linfeng Cun, Jin Zhu, Jingen Deng and Jian Liao* “A C2-Symmetric Chiral Bis-Sulfoxide Ligand in Rhodium-Catalyzed Reaction: Asymmetric 1, 4- Addition of Sodium Tetraarylborates to Chromenones” J. Am. Chem. Soc. 2010, 132，4552. (Highlight by Synfacts, 2010, 790.)
(12) Feng Lang, Dong Li, Junmin Chen, Jun Chen, Liangchun Li, Linfeng Cun, Jin Zhu, Jingen Deng and Jian Liao* “tert-Butanesulfinylphosphines: Simple Chiral Ligands in Rhodium-Catalyzed Asymmetric Addition of Arylboronic Acid to Electron-Deficient olefins” Adv. Synth & Catal. 2010, 352, 843. ( Highlight by Synfacts, 2010, 667)
(11) 廖建，邓金根 《不对称催化新概念与新方法》，（丁奎岭、范青华主编）第20章：不对称催化—从学术研究到工业应用（典型案例分析）。2009年，化学工业出版社。
(10) Peng Wang, Junmin Chen, Linfeng Cun, Jingen Deng, Jin Zhu and Jian Liao* “Aryl tert-Butyl Sulfoxide-Promoted Highly Enantioselective Addition of Allyltrichlorosilane to Aldehydes”Org. Biomol. Chem., 2009, 7, 3741.
(9) Xiaoyu Guan, Zhangqin Liu, Haoxi Huang, Liping Yang, Jian Liao* and Wenhao Hu* “Novel C–S Bond Formation Through a’,b-Elimination of tert-Butyl Sulfoxonium Ylides: A Facile Approach to Chiral Sulfoxides” Synlett. 2009, 2183. （与华东师大胡文浩教授合作）
(8) Junmin Chen, Feng Lang, Dong Li, Linfeng Cun, Jin Zhu, Jingen Deng, Jian Liao* “Palladium-catalyzed asymmetric allylic nucleophilic substitution reactions using chiral tert-butanesulfinylphosphine ligands” Tetrahedron: Asymmetry 2009, 20, 1953.(Highlight by Synfact, 2009, 1374).
(7) Dong Li, Jingen Deng, Jin Zhu, Jian Liao* “Synthesis of 3,3'-Substituted Biphenyl and Binaphthyl-based Phosphoramidite Ligands” Chin. Synth. Chem. 2008, 16, 656.
(6) Junmin Chen, Dong Li, Haifeng Ma, Linfeng Cun, Jin Zhu, Jingen Deng, Jian Liao* “Catalytic asymmetric synthesis of α- branched chiral amines using a novel chiral tert-butanesulfinylphosphine ligand”Tetrahedron Lett. 2008. 49. 6921.
(5) P. Harshad; J. Liao; R. Hedden* “Smectic Ordering in Main-Chain Siloxane Polymers and Elastomers Containing p-Phenylene Terephthalate Mesogens” Macromolecules 2007, 40, 6206.
(4) J. Liao; Qing Wang * “Ruthenium-Catalyzed Knoevenagel Condensation: A New Route toward Cyano-Substituted Poly(p-phenylenevinylene)s” Macromolecules 2004, 37, 7061.
(3) J. Liao; X. X. Sun; X. Cui; K. B. Yu; J. Zhu; J. G. Deng* “Facile optical resolution of tert-butanethiosulfinate by molecular complexation with (R)-BINOL and study of chiral discrimination of the diastereomeric complexes” Chem. Eur. J. 2003, 9, 2611.
(2) J. Liao; X. H. Peng; J. H. Zhang; K. B. Yu; X. Cui; J. Zhu; J. G. Deng* “Facile resolution of racemic terbutaline and a study of molecular recognition through chiral supramolecules based on enantiodifferentiating self-assembly” Org. & Biomol. Chem. 2003, 1, 1080.
(1) J. H. Zhang, J. Liao, X. Cui, K. B. Yu, J. Zhu, J. G. Deng*, S. F. Zhu, L. X. Wang, Q. L. Zhou*, L. W. Chung, T. Ye* “Highly Efficient and practical resolution of 1,1’-spirobiindane-7,7’-diol by inclusion crystallization with N-benzylcinchonidinium chloride” Tetrahedron: Asymmetry 2002, 13, 1363.
Supported Projects
National Basic Research Program of
West Light Foundation of CAS, 2008.