Chinese | CAS
Ma Xiaofeng
Highest   Education:Ph.D

Education and Appointments:


  September 2007-July 2012 Ph. D. (Medicinal chemistry), Chengdu Institute of Biology, Chinese Academy of Sciences. Ph.D. Advisor: Professor: Hua-Wu Shao

  September 2003-July 2007,Bachelor of Medicine (Pharmacy),Department of Pharmacy, Lanzhou University, China


  From September 2019, Professor, Chengdu Institute of Biology, Chinese Academy of Sciences (CAS)

  March 2016-March 2019,Postdoctoral Associate,School of Chemsitry, University of Brsitol, UK, Supervisor: Prof. John F. Bower

  July 2012-October 2012,Research Assistant, Chengdu Institute of Biology, Chinese Academy of Sciences (CAS),Supervisor: Prof. Hua-Wu Shao

Research Interest

  Carbohydrate Chemistry, Medicinal Chemistry, Asymmetric Catalysis and Synthesis

Public Services


Seleted Publication

  [1] Xiaofeng Ma*, Yazhou Liu, Le Du, Jingwei Zhou, István E. Markó, Post-Functionalization of Dibenzothiophene?to Functionalized Biphenyls via a Photoinduced?Thia-Baeyer-Villiger Oxidation, Nat. Commun. 2020, 11, 914-923.

  [2] Xiaofeng Ma, Ian R. Hazelden, Thomas Langer, Rachel H. Munday, John F. Bower*, Enantioselective Aza-Heck Cyclizations of?N_x005f(Tosyloxy)carbates: Synthesis of Pyrrolidines and Piperidines, J. Am. Chem. Soc. 2019, 141, 3356-3360. (Highlight in Synfacts, 2019, 15, 0483).

  [3] Xiaofeng Ma*, Damien F. Dewez, Le Du, Xiya Luo, István E. Markó, Kevin Lam*, Synthesis of Diketones, Ketoesters and Tetraketones by Electrochemical Oxidative Decarboxylation of Malonic Acid Derivatives: Application to the Synthesis of?cis-Jasmone, J. Org. Chem. 2018, 83, 12044-12055.

  [4] Xiaofeng Ma, Joshua J. Farndon, Tom A. Young, Natalie Fey, John F. Bower*, A Simple and Broadly Applicable C-N Bond Forming Dearomatization Protocol Enabled by Bifunctional Amino Reagents, Angew. Chem. Int. Ed. 2017, 56, 14531-14535. (Highlight in Org. Process Res. Dev. 2017, 21, 1873-1883).

  [5] Ian R. Hazelden,# Xiaofeng Ma,# (#Co-first author) Thomas Langer, John F. Bower*, Diverse N-Heterocyclic Ring Systems?via?Aza-Heck Cyclizations of? N-(Pentafluorobenzoyloxy) sulfonamides, Angew. Chem. Int. Ed. 2016, 55, 11198-11202.

  [6] Xiaofeng Ma, Hodney Lubin, Enik? Ioja, Orsolya Kékesi, ?gnes Simon, ?gota Apáti, Tamás I. Orbán, László Héja, Julianna Kardos, István E. Markó*, Straightforward and Effective Synthesis of γ-Aminobutyric Acid Transporter Subtype 2-Selective Acyl-substituted Azaspiro[4.5]decanes, Bioorg. Med. Chem. Lett. 2016, 26, 417-423.

  [7] Xiaofeng Ma, Xiya Luo, Simon Dochain, Charlotte Mathot, István E. Markó*, Electrochemical Oxidative Decarboxylation of Malonic Acid Derivatives: A Method for the Synthesis of Ketals and Ketones, Org. Lett.?2015,?17, 4690-4693. IF: 6.555 (2018). (Featured on Organic Chemistry Portal, chemistry. Org/ abstracts /lit5/128.shtm).

  [8] Xiaofeng Ma, Jichao Zhang, Qin Tang, Jun Ke, Wei Zou, Huawu Shao*, Stereospecific [3+2] Cycloaddition of 1,2-Cyclopropanated Sugars and Ketones Catalyzed by SnCl4: An Efficient Synthesis of Multi-Substituted Perhydrofuro[2,3-b]furans and Perhydrofuro[2,3-b]pyrans,?Chem. Commun.?2014,?50, 3505- 3508.

  [9] Xiaofeng Ma, Qin Tang, Jun Ke, Jichao Zhang, Xinglong Yang, Xudong Shen, Huawu Shao*, A Neighboring Group Participation Strategy: Direct and Highly Diastereoselective Synthesis?of 2-Substituted and 2,2-Bisubstituted Perhydrofuro[2,3-b]pyran Derivatives,?Org. Biomol. Chem.?2014,?12, 7381-7388.

  [10] Xiaofeng Ma, Qin Tang, Jun Ke, Jichao Zhang, Cong Wang, Haibo Wang, Yuxue Li*, Huawu Shao*, Straightforward and Highly Diastereoselective Synthesis of 2,2-Di-Substituted Perhydrofuro [2,3-b]pyran (and furan) Derivatives Promoted by BiCl3, Chem. Commun.?2013,?49, 7085-7087 (Highlight in?Synfacts,?2013, 9, 1212).

  [11] Xiaofeng Ma,?Qin Tang,?Jun Ke,?Xinglong Yang, Jichao Zhang, Huawu Shao*, InCl3?Catalyzed Highly Diastereoselective [3+2] Cycloaddition of 1,2-Cyclopropanated Sugars with Aldehydes: A Straightforward Synthesis of Persubstituted?Bis-Tetrahydrofurans and Perhydrofuro[2,3-b]pyrans, Org. Lett.?2013,?15, 5170-5173.

  [12] Xiaofeng Ma, Qiang Tian, Qin Tang,?Jinzhong Zhao, Huawu Shao*, A Novel and Highly Stereoselective Synthesis of 2-Substituted Perhydrofuro[2,3-b]pyran Derivatives,??Org. Lett.?2011, 13, 4276-4279.

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