廖循 职 务: 职 称:研究员 学 历:博士研究生
电 话:82890402;18010696109 传 真:028-82890288 通讯地址:四川省成都市人民南路四段9号
邮政编码:610041 电子邮件:liaoxun@cib.ac.cn

个人简历

     廖循,博士,研究员,博士生导师。

     1994年本科毕业于西南师范大学

     2000年于浙江大学化学系获得博士学位,入中国科学院成都生物研究所工作至今,现为所学位委员会委员。

     主持国家自然科学基金、中组部-中科院“西部之光”人才计划、中国科学院战略生物资源项目、四川省重点科技项目等各类科技项目20多项。

     在包括Analytical Chimica Acta, Journal of Agriculture and Food Chemistry, Food Chemistry, Journal of Chromatography A, Material Science and Engineering C等著名学术期刊发表SCI论文50多篇, 为20多个国际学术期刊审稿人;申请15件专利,获得授权8件。

研究方向

      天然药物化学;中药化学;分析化学

社会任职及荣誉(含获奖)

     
     

承担科研项目情况

      国家自然科学基金委面上项目

      中科院“西部之光”人才计划

      中科院STS项目

      四川省应用基础重大研究项目

代表论著

      1. YK Hu, XL Bai, H Yuan, Y Zhang, X Liao*. Polyphenolic glycosides from the fruits extract of Lycium ruthenicum Murr and their monoamine oxidase B inhibitory and neuroprotective activities. Journal of Agricultural and Food Chemistry, 2022, 10.1021/acs.jafc.2c02375.

      2. XW Qi, YM Liu *, YK Hu, H Yuan, EA Ayeni, X Liao*. Ligand fishing based on tubular microchannel modified with monoamine oxidase B for screening of the enzyme's inhibitors from Crocus sativus and Edgeworthia gardneri.Journal of Separation Science,2022, 10.1002/jssc.202200057.

      3. MY Wang, X Liao*, PB Tchounwou, YM Liu*. Coupling a droplet generator with conventional ESI–MS for quantitative analysis of small?volume samples. Analytical and Bioanalytical Chemistry, 2022, DOI:10.1007/s00216-021-03808-4.

      4. EA Ayeni, YZ Gong, H Yuan, YK Hu, XL Bai, X Liao*. Medicinal plants for anti-neurodegenerative diseases in West Africa. Journal of Ethnopharmacology, 2022, 285:114468.

      5. Y Zhao, JJ Hu, XL Bai, HP Liu, XW Qi, X Liao*. Fast screening of tyrosinase inhibitors from traditional Chinese medicinal plants by ligand fishing in combination with in situ fluorescent assay. Analytical and Bioanalytical Chemistry, 2022, DOI: 10.1007/s00216-021-03864-w.  

      6. Y Zhao, XL Bai, T Song, GL Zhang, YC Yuan, YM Liu*, X Liao*. Determination of environmental estrogens and bisphenol A in water samples by ultra-high performance liquid chromatography coupled to Q-Exactive high resolution mass spectrometry after magnetic solid-phase extraction. Microchemical Journal, 2019, DOI: j.microc.2019.104212

      7. Y Zhao, YC Yuan, XL Bai, YM Liu*, GF Wu, FS Yang, X Liao*. Multi-mycotoxins analysis in liquid milk by UHPLC-Q-Exactive HRMS after magnetic solid-phase extraction based on PEGylated multi-walled carbon nanotubes. Food Chemistry, 2019, DOI: foodchem.2019.125429

      8. GF Wu, XL Jiang, YZ Gong, YD Hu, XL Bai, X Liao*. Ligand fishing of anti-neurodegenerative components from Lonicera japonica using magnetic nanoparticles immobilised with monoamine oxidase B. Journal of Separation Science, 2019, 42:1117-1298.

      9. XL Jiang, YC Yuan, LB Chen, YM Liu*, MW Xiao, YD Hu, Z Chun, X Liao*. Monoamine oxidase B immobilized on magnetic nanoparticles for screening. Microchemical Journal, 2019, 146:1181-1189.

      10. MW Xiao, XL Bai, YM Liu, L Yang, X Liao*. Simultaneous determination of trace Aflatoxin B1 and Ochratoxin A by aptamer-based microchip capillary electrophoresis in food samples. Journal of Chromatography A, 2018, 1569: 222-228.

      11. MW Xiao, XL Bai, YM Liu, L Yang, X. YD Hu, X Liao*. Rapid quantification of aloin A and B in aloe plants and aloe-containing beverages and pharmaceutical preparations by microchip capillary electrophoresis with laser induced fluorescence detection. Journal of Separation Science. 2018, 41: 3772-3781.

      12. HD Wan, B. Tang, X Liao, QF Zeng, ZH Zhang, LJ Liao. Analysis of neuronal phosphoproteome reveals PINK1 regulation of BAD function and cell death. Cell Death & Differentiation 2018, 25:904–917.

      13. Y Zhao, LH Wan, XL Bai, YM Liu, FP Zhang, YM Liu, X Liao*. Quantification of mycotoxins in vegetable oil by UPLC-MS/MS after magnetic solid-phase extraction. Food Additives & Contaminants: Part A, 2017,34:1201-1210

      14. MW Xiao, XL Bai, PL Xu, Y Zhao, YM Liu, X Liao*. Rapid determination of gizzerosine in fish meals using microchip capillary electrophoresis with laser-induced fluorescence detection. Food Additives & Contaminants: Part A. 2017,34:760-765

      15. JJ Hu, XL Bai, YM Liu, X Liao*. Functionalized carbon quantum dots with dopamine for tyrosinase activity analysis. Analytica Chimica Acta, 2017, 995: 99-105

      16. H Wan, B Zhang, XL Bai, Y Zhao, MW Xiao, X Liao*. Extraction of ochratoxin A in red wine with dopamine-coated magnetic multi-walled carbon nanotubes. Journal of Separatioin Science 2017, 40: 4022–4031.

      17. Q Zeng, YM Liu, YW Jia, LH Wan, X Liao*. PEGylation of magnetic multi-walled carbon nanotubes for enhanced selectivity of dispersive solid phase extraction. Materials Science and Engineering C 2017, 71: 186-194

      18. LH Wan, XL Jiang, YM Liu, JJ Hu, X Liao*. Screening of lipase inhibitors from Scutellaria baicalensis extract using lipase immobilized on magnetic nanoparticles and study on the inhibitory mechanism. Analytical and Bioanalytical Chemistry. 2016; 408:2275–2283.

      19. YW Jia, ZQ Zeng, HL Shi, YM Liu, YX Tang, X Liao*. Characterization of in vitro metabolites of irisflorentin by rat liver microsomes using high performance liquid chromatography coupled with tandem mass spectrometry. Biomedical Chromatography. 2016; 30: 1363–1370.

      20. YT Zhu, XY Ren, L Yuan, YM Liu, X Liao*. Fast identification of lipase inhibitors in oolong tea by using lipase functionalised Fe3O4 magnetic nanoparticles coupled with UPLC–MS/MS. Food Chemistry, 2015, 173: 521-526.

      21. L Yuan, PL Xu, Q Zeng, YM Liu, X Liao*. Preparation of ds-DNA functionalized magnetic nanobaits for screening of bioactive compounds from medicinal plant. Materials Science and Engineering C, 2015, 56: 401-408.

      22. HL Shi, YW Jia, SL Peng, X Liao*, YM Liu*. Metabolic study of Angelica dahurica extracts using a reusable liver microsomal nanobioreactor by liquid chromatography–mass spectrometry. Biomedical Chromatography, 2015, 29: 1514-1521.

      23. Q Zeng, YW Jia, PL Xu, MW Xiao, YM Liu, SL Peng, X Liao*. Quick and selective extraction of Z-ligustilide from Angelica sinensis using magnetic multiwalled carbon nanotubes. Journal of Separation Science, 2015, DOI 10.1002/jssc.201500862

      24. YT Zhu, XY Ren, L Yuan, YM Liu, Xun Liao*. Fast identi?cation of lipase inhibitors in oolong tea by using lipase functionalised Fe3O4 magnetic nanoparticles coupled with UPLC–MS/MS. Food Chemistry, 2015, 173: 521–526 (top journal)

      25. YT Zhu, YW Jia, YM Liu, Xun Liao*. Lipase ligands in Nelumbo nucifera leaves and study of their binding mechanism. Journal of Agricultural and Food Chemistry, 2014, 62: 10679-10686

      26. YT Zhu, XY Ren, YM Liu*, Xun Liao*. Covalent immobilization of porcine pancreatic lipase on carboxyl-activated magnetic nanoparticles: Characterization and application for enzymatic inhibition assays. Materials Science and Engineering C, 2014, 38: 278-285.