青琳森，男，1981年9月生，四川南充人，执业药师，副研究员、硕士生导师
教育经历：
1999.9 - 2003.6 华西医科大学，药学院，药学专业本科
2003.9 - 2006.6 四川大学，华西药学院，生药学专业硕士
2008.9 - 2011.6 中国科学院成都生物研究所，药物化学专业博士
工作经历：
2006.7 - 2008.8 成都地奥制药集团，药物研究所
2011.7 - 2013.6 中国科学院成都生物研究所，博士后
2013.7至今 中国科学院成都生物研究所，副研究员
天然活性成分研究与新药开发
四川省药学会中药与天然药专委会委员
四川省分析测试学会有机质谱专委会理事
中国人民政治协商会议成都市第十六届委员会委员
主持：
1. 中央引导地方科技发展资金项目，2022.9-2023.8
2. 四川省科技计划国际/港澳台科技创新合作项目，2022.1-2023.12
3. 中国科学院战略生物资源服务网络计划活性天然化合物发现、评价与转化平台项目，2021.10-2024.12
4. 浙江佐力药业股份有限公司委托项目，2021.3-2024.3
5. 四川省科技计划重点研发项目，2019.1-2020.12
6. 中国科学院西部青年学者（院内A类）项目，2019.1-2021.12
7. 中国科学院战略生物资源服务网络计划活性天然化合物发现、评价与转化平台项目，2018.8-2021.7
8. 中国博士后科学基金第6批特别资助，2013.6-2016.6
9. 中国科学院西部博士人才培养计划，2013.1-2016.6
10. 国家自然科学基金青年基金，2013.1-2015.12
11. 中国博士后科学基金第50批面上资助，2011.9-2013.12
同时参与国家自然科学基金、四川省科技计划、香港特区政府卫生署项目、澳门科学技术发展基金等多项课题的研究。
科研论文（一作/通讯，含并列）：
1. Lin-Sen Qing, et al. Microfluidic strategies for natural products in drug discovery: Current status and future perspectives. Trends in Analytical Chemistry, 2023, 158: 116832.
2. You-Jiao Wu, et al. Elucidation of the binding mechanism of astragaloside IV derivative with human serum albumin and its cardiotoxicity in zebrafish embryos. Frontiers in Pharmacology, 2022, 13: 987882.
3. Tian-Tian Wang, et al. Nanomaterial-based optical- and electrochemical-biosensors for urine glucose detection: A comprehensive review. Advanced Sensor and Energy Materials, 2022, 1(3): 100016
4. Qian-Long Wang, et al. Non-invasion prognosis of post-myocardial infarction using urinary miRNA ultra-trace detection based on single target DNA functionalized AuNPs. ACS Applied Materials & Interfaces, 2022, 14(3): 3633-3642.
5. Ming-Qing Tang, et al. Advances in aptamer-based sensing assays for C-reactive protein. Analytical and Bioanalytical Chemistry, 2022, 414(2): 867-884.
6. Jing Xie, et al. Determination of nine nucleosides in Rhizoma Paridis by quantitative analysis of multi-components via a single marker method. Journal of Separation Science, 2021, 44(9): 1866-1874.
7. Li Chen, et al. Astragaloside IV derivative (LS-102) alleviated myocardial ischemia reperfusion injury by inhibiting Drp1Ser616 phosphorylation-mediated mitochondrial fission. Frontiers in Pharmacology, 2020, 11: 1083.
8. Ming-Qing Tang, et al. Research progress of C-reactive protein analysis. Chinese Journal of Analytical Chemistry, 2020, 48(9): 1121-1130.
9. Tian-Tian Wang, et al. A feasible image-based colorimetric assay using a smartphone RGB camera for point-of-care monitoring of diabetes. Talanta, 2020, 206: 120211.
10. Qian-Long Wang, et al. Colorimetric determination of the early biomarker hypoxia-inducible factor-1 alpha (HIF-1α) in circulating exosomes by using a gold seed-coated with aptamer-functionalized Au@Au core-shell peroxidase mimic. Microchimica Acta, 2020, 187(1): 61.
11. Chao-Xi Chen, et al. A new strategy for the preparation of antibody against natural glycoside: With astragaloside IV as an example. Fitoterapia, 2020, 142: 104488.
12. Ying Xue, et al. Determination of flavonoid glycosides by UPLC-MS to authenticate commercial lemonade. Molecules, 2019, 24(16): 3016.
13. Qian-Long Wang, et al. Competitive protein binding assay of naproxen by human serum albumin functionalized silicon dioxide nanoparticles. Molecules, 2019, 24(14): 2593.
14. Ying Xue, et al. UPLC-QqQ/MS combined with similarity assessment of 17 nucleic acid constituents in 147 edible fungi from Sichuan Basin, China. Food Research International, 2019, 120: 577-585.
15. Lin-Sen Qing, et al. Pharmacokinetics comparison, intestinal absorption and acute toxicity assessment of a novel water-soluble astragaloside IV derivative (astragalosidic acid, LS-102). European Journal of Drug Metabolism and Pharmacokinetics, 2019, 44(2): 251-259.
16. Wen-Xia Sun, et al. Determination of a astragaloside IV derivative LS-102 in plasma by ultra-performance liquid chromatography-tandem mass spectrometry in dog plasma and its application in a pharmacokinetic study. Phytomedicine, 2019, 53: 243-251.
17. Ying Xue, et al. Quality evaluation of Tricholoma matsutake based on the nucleic acid compounds by UPLC-TOF/MS and UPLC-QqQ/MS, Molecules, 2019, 24(1): 34.
18. Jing Xie, et al. A efficient method to identify cardioprotective components of Astragali Radix using a combination of molecularly imprinted polymers-based knockout extract and activity evaluation. Journal of Chromatography A, 2018, 1576: 10-18.
19. Chu Chen, et al. Neutral loss scan - based strategy for integrated identification of amorfrutin derivatives, new peroxisome proliferator-activated receptor gamma agonists, from Amorpha Fruticosa by UPLC-QqQ-MS/MS and UPLC-Q-TOF-MS. Journal of The American Society for Mass Spectrometry, 2018, 29(4): 685-693.
20. Ying Xue, et al. Optimization of vortex-assisted dispersive liquid-liquid microextraction for the simultaneous quantitation of eleven non-anthocyanin polyphenols in commercial blueberry using the multi-objective response surface methodology and desirability function approach. Molecules, 2018, 23(11): 2921.
21. Lin-Sen Qing, et al. Astragalosidic acid: a new water-soluble derivative of astragaloside IV prepared using remarkably simple TEMPO-mediated oxidation. Molecules, 2017, 22(8): 1275.
22. Qian-Long Wang, et al. An efficient direct competitive nano-ELISA for residual BSA determination in vaccines. Analytical and Bioanalytical Chemistry, 2017, 409(19): 4607-4614.
23. Qian-Long Wang, et al. Development of a nano-SiO2 based enzyme-linked ligand binding assay for the determination of ibuprofen in human urine. Talanta, 2017, 167: 617-622.
24. Qian-Long Wang, et al. A simple nano-SiO2 based ELISA method for residue detection of 2,4-dichlorophenoxyacetic acid in bean sprouts. Food Analytical Methods, 2017, 10(5): 1500-1506.
25. Jing Xie, et al. Determination of contents of catechins in oolong teas by quantitative analysis of multi-components via a single marker (QAMS) method. Food Analytical Methods, 2017, 10(2): 363-368.
26. Lin-Sen Qing, et al. A rapid study of botanical drug-drug interaction with protein by re-ligand fishing using human serum albumin-functionalized magnetic nanoparticles. Natural Product Communications. 2015, 10(12): 2161-2163.
27. Jing Xie, et al. A novel rhein-functionalized resin with application for the preconcentration of anthraquinones. Analytical Letters. 2014, 47(14): 2332-2340.
28. Lin-Sen Qing, et al. Rapid magnetic solid-phase extraction for the selective determination of isoflavones in soymilk using baicalin-functionalized magnetic nanoparticles. Journal of Agricultural and Food Chemistry, 2013, 61(34): 8072-8078.
29. Lin-Sen Qing, et al. Identification of flavonoid glycosides in Rosa chinensis flowers by liquid chromatography–tandem mass spectrometry in combination with 13C nuclear magnetic resonance. Journal of Chromatography A, 2012, 1249: 130-137.
30. Lin-Sen Qing, et al. Identification of enzyme inhibitors using therapeutic target protein-magnetic nanoparticle conjugates. Analytical Methods, 2012, 4(6): 1612-1615.
31. Lin-Sen Qing, et al. Using baicalin-functionalized magnetic nanoparticles for selectively extracting flavonoids from Rosa chinensis. Journal of Separation Science, 2011, 34(22): 3240-3245.
32. Lin-Sen Qing, et al. Ligand fishing with functionalized magnetic nanoparticles coupled with mass spectrometry for herbal medicine analysis. Analytical and Bioanalytical Chemistry, 2011, 399(3): 1223-1231.
33. Lin-Sen Qing, et al. Rapid probe and isolation of bioactive compounds from Dioscorea panthaica using human serum albumin functionalized magnetic nano-particles (HSA-MNPs)-based ligand fishing coupled with electrospray ionization mass spectrometry. Rapid Communications in Mass Spectrometry, 2010, 24(22): 3335-3339.
34. Lin-Sen Qing, et al. Ligand fishing from Dioscorea nipponica extract using human serum albumin functionalized magnetic nanoparticles. Journal of Chromatography A, 2010, 1217(28): 4663-4668.
授权专利（第一发明人）：
1. 黄芪苷酸盐的一步制备法，专利号ZL 202010472785.8
2. 黄芪甲苷人工抗原及其人工抗体的制备方法和应用，专利号ZL201910034969.3
3. 一种简易的尿糖定量检测方法以及尿糖定量检测试剂盒，专利号ZL201910462578.1
4. 黄芪苷酸及其衍生物在制备抗血栓药物中的应用，专利号ZL201711019204.X
5. 一种伏立康唑的合成方法，专利号ZL201610984653.7
6. 一种黄芪甲苷衍生物及其制备方法和应用，专利号ZL201611166597.2
7. 山菅兰的活性提取物及其制备方法和应用，专利号ZL201610187409.8
8. 一种牛血清白蛋白检测探针及其制备方法和应用，专利号ZL201610986773.0
9. 一种基于玻璃毛细管的牛血清白蛋白检测探针及其制备方法和应用，专利号ZL201610987386.9
10. 一种表面键合黄芩苷磁性纳米粒子及其制备方法和用途，专利号ZL201010545352.7